Recent Publications


Genomic evolution shapes prostate cancer disease type
Genomic, Bioinformatic, Cancer Aleks Genomic, Bioinformatic, Cancer Aleks

Genomic evolution shapes prostate cancer disease type

Dan J Woodcock, Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas J Gruber, Aleksandra Ziubroniewicz, Gunes Gundem, Yaobo Xu, Adam Butler, Ezequiel Anokian, Bernard J Pope, Chol-Hee Jung, Maxime Tarabichi, Stefan C Dentro, J Henry R Farmery, Peter Van Loo, Anne Y Warren, Vincent Gnanapragasam, Freddie C Hamdy, G Steven Bova, Christopher S Foster, David E Neal, Yong-Jie Lu, Zsofia Kote-Jarai, Michael Fraser, Robert G Bristow, Paul C Boutros, Anthony J Costello, Niall M Corcoran, Christopher M Hovens, Charlie E Massie, Andy G Lynch, Daniel S Brewer, Rosalind A Eeles, Colin S Cooper, David C Wedge. Cell Genomics 2024/3/13 https://www.cell.com/cell-genomics/fulltext/S2666-979X(24)00038-7

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Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome
Genomic, Bioinformatic, Cancer Aleks Genomic, Bioinformatic, Cancer Aleks

Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome

Yujie Jiang, Matthew D Montierth, Kaixian Yu, Shuangxi Ji, Shuai Guo, Quang Tran, Xiaoqian Liu, Seung Jun Shin, Shaolong Cao, Ruonan Li, Yuxin Tang, Tom Lesluyes, Scott Kopetz, Jaffer Ajani, Pavlos Msaouel, Sumit K Subudhi, Ana Aparicio, Padmanee Sharma, John Paul Shen, Anil K Sood, Maxime Tarabichi, Jennifer R Wang, Marek Kimmel, Peter Van Loo, Hongtu Zhu, Wenyi Wang. bioRxiv 2024.07. 03.601939 https://www.biorxiv.org/content/10.1101/2024.07.03.601939v1.abstract

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Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells
Transcriptomic, Thyroid, Cancer, Organoids Aleks Transcriptomic, Thyroid, Cancer, Organoids Aleks

Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells

Adrien Tourneur, Joel Rodrigues Vitoria, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frederick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours. bioRxiv 2024.02. 15.580495 https://www.biorxiv.org/content/10.1101/2024.02.15.580495v2.abstract

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Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit absorptive and barrier alterations
Organoids, Gut Aleks Organoids, Gut Aleks

Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit absorptive and barrier alterations

Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia, Gastro Hep Advances, 2024, 100599, ISSN 2772-5723, https://doi.org/10.1016/j.gastha.2024.100599.

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STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179

STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179

Grasberger H, Dumitrescu A M, Liao X-H, Swanson E G, Weiss R E, Srichomkwun P, Pappa T, Chen J, Yoshimura T, Hoffmann P, França M M, Tagett R, Onigata K, Costagliola S, Ranchalis J, Vollger M R, Stergachis A B, Chong J X, Bamshad M J, Smits G, Vassart G and Refetoff S, Nature Genetics (2024) https://doi.org/10.1038/s41588-024-01717-7

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Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
Thyroid cancer, Braf, Organoids Aleks Thyroid cancer, Braf, Organoids Aleks

Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

H. Lasolle, A. Schiavo, A. Tourneur, P. Gillotay, B. de F. da Fonseca, L. Ceolin, O. Monestier, B. Aganahi, L. Chomette, M. M. L. Kizys, L. Haenebalcke, T. Pieters, S. Goossens, J. Haigh, V. Detours, A. L. S. Maia, S. Costagliola, and M. Romitti, Oncogene 1–16 (2023) doi:10.1038/s41388-023-02889-y.

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