Transcriptomics of autoimmune diseases identifies FGFR1 as a target for pancreatic β-cell protection

Yi X, Zimath PL, Martin-Vazquez E, Oliveira JG, Jawurek S, Title AC, Yesildag B, Mourad NI, Buemi A, Pattou F, Kerr-Conte J, Costagliola S, Romitti M, Eizirik DL. (2025)

https://doi.org/10.1016/j.jaut.2025.103469

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Autophagy inhibition improves sensitivity to the multi-kinase inhibitor regorafenib in preclinical mouse colon tumoroids