PhD Position
Cellular and development biology
Project EMBARK: exploring how Extra-embryonic Mesoderm-derived structures provide Baby Assistance through the Robustness of Keratins (EMBARK).
EMBARK is centred on the molecular, cellular and functional characterisation of extra-embryonic mesoderm (ExM) and its derived tissues, the extra-embryonic envelopes, in mouse and human. Defects in ExM-derived tissues are associated with pathologies of the pregnancy, such as foetal growth restriction, placental insufficiency and pre-eclampsia. Understanding the molecular and cellular processes underlying ExM formation and function may reveal therapeutic targets.
Qualification profile
We wish to recruit a PhD student with a background in engineering and/or bioinformatics. Those skills would greatly complement our skills in developmental and stem cell biology. The student will collaborate with PhD students in the labs of Isabelle Migeotte and Anchel De Jaime Soguero to develop innovative methods to explore the mechanics of extra-embryonic cells and tissues, integrate multiple types of -omics data and ultimately attempt to fine tune mouse and human germ layer, tissue and embryo stem cells-based models to tackle aspects of human ExM biology.
We offer
Funding is available for four years. The students would nonetheless be expected to apply to a fellowship (FRIA/Aspirant/BKF PhD fellowships) at the end of the first year.
Why to join IRIBHM and come to live in Brussels?
IRIBHM-J.E. Dumont is a multidisciplinary research institute at the Université Libre de Bruxelles (ULB, Belgium) with a focus in signal transduction, development, neuroscience, cancer and computational biology (https://iribhm.org). At the heart of Europe, Brussels is the largest student city in Belgium welcoming 160 different nationalities, a vibrant, tolerant and international capital.
How to apply:
Send your application to Isabelle Migeotte (Isabelle.Migeotte@ulb.be) and Anchel Soguero (anchel.de.jaime.soguero@ulb.be), with the subject lane: EMBARK application. Attach: (1) Your BSc and MSc transcripts, (2) a detailed CV, (3) the contact information of two previous mentors/supervisors, and (4) a cover letter stating your personal interest in our lab and project.
